Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities by Deberardinis, Ralph J.

Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities

Cancer cells often display metabolic changes that distinguish them from normal cells in the body. Their preference...
¥11,935 JPY
¥11,935 JPY
SKU: 9781621824701
Product Type: Books
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Author: Ralph J. Deberardinis
Format: Hardcover
Language: English
Subtotal: ¥11,935
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Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities by Deberardinis, Ralph J.

Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities

¥11,935

Cancer Metabolism: Historical Landmarks, New Concepts, and Opportunities

¥11,935
Author: Ralph J. Deberardinis
Format: Hardcover
Language: English
Cancer cells often display metabolic changes that distinguish them from normal cells in the body. Their preference for glycolysis over aerobic respiration even in the presence of oxygen was first observed over a century ago; however, it is only over the past two decades that researchers have begun to characterize all the pathways involved and investigate the therapeutic possibilities. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews our understanding of the diversity of metabolic changes seen in cancer cells and their roles in sustaining tumor survival and proliferation. The contributors cover the new technologies being used to monitor metabolism in cells, the Warburg effect and the importance of mitochondria, metabolic signaling, and the importance of redox reactions and antioxidants. Other chapters examine the role of the tumor microenvironment, metal ions, and the immune system. The book also discusses the role of diet and how studies of patients are revealing how metabolic reprogramming occurs. It will thus be of interest not only to biochemists and oncologists but to all biologists interested in how the behavior of cells is regulated and coordinated.

Author: Ralph J. Deberardinis, Karen Vousden, Navdeep Chandel
Publisher: Cold Spring Harbor Laboratory Press
Published: 11/19/2024
Pages: 438
Binding Type: Hardcover
Weight: 2.74lbs
Size: 10.00h x 7.00w x 1.31d
ISBN: 9781621824701

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