Organocatalytic Dynamic Kinetic Resolution by Pellissier, Hélène

Organocatalytic Dynamic Kinetic Resolution

In a classical kinetic resolution, two enantiomers of a racemate are transformed into chiral products at different...
¥60,372 JPY
¥60,372 JPY
SKU: 9781839165658
Product Type: Books
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Author: Hélène Pellissier
Format: Hardcover
Language: English
Subtotal: ¥60,372
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Organocatalytic Dynamic Kinetic Resolution by Pellissier, Hélène

Organocatalytic Dynamic Kinetic Resolution

¥60,372

Organocatalytic Dynamic Kinetic Resolution

¥60,372
Author: Hélène Pellissier
Format: Hardcover
Language: English

In a classical kinetic resolution, two enantiomers of a racemate are transformed into chiral products at different rates with a maximum theoretical yield of 50%. However, the need to reduce costs and waste in synthesis have led to efforts to develop novel resolution procedures proceeding beyond this 50% limited yield. This has led to the evolution of classical kinetic resolution into dynamic kinetic resolution (DKR), allowing a quantitative yield of one of the enantiomers. DKR combines the resolution step of kinetic resolution with an in-situ racemization of the chirally-labile substrate. It is only in the last two decades that chiral green organocatalysts have been demonstrated to be capable of promoting DKRs considerably expanding the synthetic scope of the powerful concept of DKR.

Collecting all the developments in the field of DKR, this book shows that a wide variety of organocatalysts allow excellent levels of stereocontrol and yields in many types of transformations. It is a great resource for academics and industrialists interested in green enantioselective catalytic reactions.



Author: Hélène Pellissier
Publisher: Royal Society of Chemistry
Published: 05/06/2022
Pages: 158
Binding Type: Hardcover
Weight: 0.90lbs
Size: 9.30h x 6.20w x 0.60d
ISBN: 9781839165658

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