An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks

This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks--a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields.

Key Features:

• A hands-on approach to modelling
• Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models
• Thoughtful exercises to test and enable understanding of concepts
• State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design
• Emphasis on coding and software tools for systems biology
• Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https: //ramanlab.github.io/SysBioBook/

An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.

Dr. Karthik Raman is an Associate Professor at the Department of Biotechnology, Bhupat & Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras. He co-founded and co-ordinates the Initiative for Biological Systems Engineering and is a core member of the Robert Bosch Centre for Data Science and Artificial Intelligence (RBCDSAI). He has been a researcher in the area of systems biology for the last 15+ years and has been teaching a course on systems biology for the last eight years, to (mostly) engineers from different backgrounds. His lab works on computational approaches to understand and manipulate biological networks, with applications in metabolic engineering and synthetic biology.