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SECTION 1 - Basic Concepts and Background
1. History of Clinical Cytogenetics
Steven L. Gersen
2. DNA, Chromosomes, and Cell Division
Martha B. Keagle
3. Human Chromosome Nomenclature: An Overview and Definition of Terms
Marilyn L. Slovak, Aaron Theisen, and Lisa G. Shaffer
SECTION II - Examining and Analyzing Chromosomes
4. Basic Cytogenetics Laboratory Procedures
Martha B. Keagle and Steven L. Gersen
5. The Essentials of Light Microscopy
Nathan Claxton and Stephen Ross
6. Quality Control & Quality Assurance
Martha B. Keagle
7. Instrumentation in the Cytogenetics Laboratory
Steven L. Gersen
SECTION III - Clinical Cytogenetics
8. Autosomal Aneuploidy
Jin-Chen C. Wang
9. Structural Chromosome Rearrangements
Kathleen Kaiser-Rogers and Kathleen Rao
10. Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex Development
Cynthia M. Powell
11. The Cytogenetics of Infertility
Linda Marie Randolph
12. Prenatal Cytogenetics
Linda Marie Randolph
13. The Cytogenetics of Spontaneous Abortion
Solveig M. V. Pflueger
14. Chromosome Instability
Xiao-Xiang Zhang
SECTION IV - Cancer Cytogenetics
15. The Cytogenetics of Hematologic Neoplasms
Aurelia Meloni-Ehrig
16. The Cytogenetics of Solid Tumors
Linda D. Cooley and Kathleen S. Wilson
SECTION V - Adjunct Technologies
17. Fluorescence in situ Hybridization (FISH)
Daynna J. Wolff
18. Microarray-Based Cytogenetics
Lisa G. Shaffer
SECTION VI - Beyond Chromosomes
19. Fragile X: A Family of Disorders: Changing Phenotype and Molecular Genetics
Elaine B. Spector
20. Genomic Imprinting and Uniparental Disomy
Jin-Chen C. Wang
21. Genetic Counseling
Sarah Hutchings Clark
Steven L. Gersen, Ph.D.
AmeriPath Northeast, Shelton, CT, USA
Martha B. Keagle, M.Ed.
School of Agriculture, University of Connecticut, Storrs, CT, USA
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