Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation by Verwoerd, Wynand S.
Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation by Verwoerd, Wynand S.

Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation

This monograph offers a fundamentally new approach to facilitate the study of metabolic networks in cells. It...
$360.69 AUD
$360.69 AUD
SKU: 9789811255830
Product Type: Books
Please hurry! Only 666 left in stock
Author: Wynand S. Verwoerd
Format: Hardcover
Language: English
Subtotal: $360.69
Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation by Verwoerd, Wynand S.

Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation

$360.69
Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation by Verwoerd, Wynand S.

Compact Kernel of a Metabolic Flux Balance Solution Space, The: Concepts, Algorithms and Implementation

$360.69
Author: Wynand S. Verwoerd
Format: Hardcover
Language: English
Description
This monograph offers a fundamentally new approach to facilitate the study of metabolic networks in cells. It aims to overcome the limitations of either just a single FBA solution, or an overwhelming number of extreme pathways in a realistic network. Instead it focusses on the FBA solution space and describes it in a simplified way by extracting just a bounded subspace: the Solution Space Kernel or SSK. This reduces the relevant number of flux space dimensions by orders of magnitude, and allows its location, size and shape to be characterised. It is a multi-stage process, requiring many new concepts and algorithms for manipulating polytopes in high dimensional spaces.The book introduces and develops these concepts in a pragmatic way that takes into account the difficulties of performing analyses in a flux space with dimensions counting in the hundreds or thousands. It emphasizes the details of implementation in computational code and applications to realistic models are demonstrated. For many cases, the number of constraints and flux variables that fully specify the SSK polytope is only a single or double-digit number. This allows the range of metabolic states accessible to a cell to be further interpreted geometrically in terms of a manageable set of orthogonal diameters and aspect ratios. In addition, explicit representative fluxes, giving the centre and periphery of the solution space kernel, become available for further exploration.

Author: Wynand S. Verwoerd
Publisher: World Scientific Publishing Company
Published: 10/19/2022
Pages: 250
Binding Type: Hardcover
Weight: 1.11lbs
Size: 9.00h x 6.00w x 0.63d
ISBN: 9789811255830

This title is not returnable
Shipping & Return

Returns Policy

You may return most new, unopened items within 30 days of delivery for a full refund. We'll also pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.).

You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).

If you need to return an item, simply login to your account, view the order using the "Complete Orders" link under the My Account menu and click the Return Item(s) button. We'll notify you via e-mail of your refund once we've received and processed the returned item.

Shipping

We can ship to virtually any address in the world. Note that there are restrictions on some products, and some products cannot be shipped to international destinations.

When you place an order, we will estimate shipping and delivery dates for you based on the availability of your items and the shipping options you choose. Depending on the shipping provider you choose, shipping date estimates may appear on the shipping quotes page.

Please also note that the shipping rates for many items we sell are weight-based. The weight of any such item can be found on its detail page. To reflect the policies of the shipping companies we use, all weights will be rounded up to the next full pound.

Review