The Ageless Brain: How to Sharpen and Protect Your Mind for a Lifetime

New York Times Bestseller!

From the bestselling author of The End of Alzheimer's, Dr. Dale Bredesen, comes a revolutionary new approach to preventing the onset of neurodegenerative disease and creating sustained brain health.

In recent decades, advances in medicine have changed the way we think about our health. Chronic diseases like obesity, heart disease, and diabetes can be prevented or reversed. Cancer treatment has become targeted and personalized. Gene editing will allow us to eradicate many inherited disorders. But there is one class of conditions that continues to elude researchers and cause tremendous suffering: neurodegenerative disease.

More than six million Americans live with Alzheimer's disease; by 2050, this number is projected to reach thirteen million. An additional one in ten people over the age of sixty-five have dementia, while 22 percent of older adults live with some form of cognitive impairment. And it isn't just the elderly who are afflicted; diagnosis rates are rising in younger adults, with women at a higher risk than men. For many--especially those with a genetic predisposition--this fate has seemed inevitable. Until now.

Dr. Dale Bredesen is a pioneer in the field of neurodegenerative research. Lauded for his integrative protocol, he has, in clinical studies, reversed the symptoms of Alzheimer's and dementia. He shared this information in his bestselling book, The End of Alzheimer's. But Dr. Bredesen doesn't want to only treat the symptoms of this devastating illness. He wants to prevent it from developing in the first place.

In The Ageless Brain, Dr. Bredesen will share the latest, cutting-edge science on neurodegeneration, including how misunderstandings of the disease have hindered our efforts to treat it, as well as a preventative program that readers of all ages can put into practice to optimize their cognitive health now and sustain it for years to come. This is a book for everyone who cares about their ability to stay sharp and independent for a lifetime, for those who have witnessed family members decline, and for the many readers who are beginning to experience moments of brain fog or fatigue in middle age, and are concerned about what the future may hold. Just as bestselling authors like Dr. Peter Attia and Dr. Michael Greger have offered essential guidance for maintaining overall health and longevity, Dr. Bredesen has written the only book readers need to retain their vibrant minds--and thrive for a lifetime.

Author: Dale E. Bredesen
Publisher: Flatiron Books
Published: 03/25/2025
Pages: 384
Binding Type: Hardcover
Weight: 1.20lbs
Size: 9.40h x 6.60w x 1.30d
ISBN: 9781250362599


Review Citation(s):
Publishers Weekly 03/03/2025
Booklist 04/01/2025 pg. 23

About the Author
Dale Bredesen, MD, is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer's disease. He graduated from Caltech, then earned his MD from Duke University Medical Center. He served as chief resident in neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner's laboratory at UCSF as an NIH postdoctoral fellow. He has held faculty positions at UCSF, UCLA, and the University of California, San Diego. Dr. Bredesen directed the Development, Aging and Regeneration Program at Sanford Burnham Prebys before coming to the Buck Institute in 1998 as its founding president and CEO. He is the chief medical officer of MPI Cognition.